Abstract
A number of chiral dithianes were synthesised using chiral auxiliary technology. These
were then used as acyl anion equivalents in the synthesis of chiral α-oxo-β-alkyl
and chiral α-oxo-β-aryl esters.
Key words
non-racemising oxidation - chiral aldehyde - chiral 1,3-dithiane - acyl anion equivalent
- dethioacetalisation
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<TD VALIGN="TOP">
Procedure
</TD><TD VALIGN="TOP">
%Yield
</TD><TD VALIGN="TOP">
%ee
[17
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PCC
</TD><TD VALIGN="TOP">
45
</TD><TD VALIGN="TOP">
55
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