New Double-Chain and Aromatic (α-Hydroxyalkyl)phosphorus Amphiphiles

Abstract

New double-chain bis-(α-hydroxyalkyl)phosphinic acids 1 are synthesized from NaH₂PO₂·H₂O and aliphatic aldehydes. Direct and quantitative one-pot synthesis of new 4-alkoxybenzal­dehydes 2 is realized from 1-bromoalkanes and 4-hydroxybenzaldehyde. Addition of NaH₂PO₂·H₂O to aldehydes 2 leads to the formation of the bis-adducts and also to the cleavage of the ether bond. New [α-hydroxy-(4-alkoxybenzyl)]phosphinic acids 3 are prepared by addition of aldehydes 2 to aqueous hypophosphorous acid.

Key words

aldehydes - surfactants - phosphorylations - phosphinic acids - benzaldehydes - addition reactions

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1

New address: Alice Brun, Max-Planck-Institute of Colloids and Interfaces, 14424 Potsdam, Germany; fax [phone]; e-mail [e-mail]

2

Deceased 07.03.2002.