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Der Nuklearmediziner 2002; 25(2): 101-105
DOI: 10.1055/s-2002-33279
MIBG-Szintigraphie

© Georg Thieme Verlag Stuttgart · New York

Empfehlungen zur Durchführung der MIBG- Szintigraphie bei Kindern

Leitlinie übernommen vom Paediatric Committee der European Association of Nuclear Medicine (EANM)Guidelines for MIBG-scintigraphy in childrenP.  Olivier1 , P. Colarinha2 , J. Fettich3 , S. Fischer4 , K. Hahn4 , U. Porn4 , J. Frökier5 , F. Giammarile6 , I. Gordon7 , L. Kabasakal8 , M. Mann9 , M. Mitjavila10 , A. Piepsz11 , R. Sixt 12 , J. van Velzen13
  • 1CHU Nancy, France
  • 2Instituto Portugues de Oncologia, Lisbon, Portugal
  • 3University Medical Centre Ljubljana, Slovenia
  • 4Klinik fuer Nuklearmedizin, University of Munich, Germany
  • 5Aarhus University Hospital - Skejby, Denmark
  • 6Centre Léon Bérard, Lyon, France
  • 7Great Ormond Street Hospital for Children, London, UK
  • 8Cerraphasa Tipp Fakultesi, Nukleer Tipp Ana Bilim Dali, Aksaray, Turkey
  • 9Red Cross Hospital Cape Town, South Africa
  • 10Hospital Universitário de Getafe, Madrid, Spain
  • 11AZ VUB and CHU St Pierre, Brussels, Belgium
  • 12Sahlgrenska University Hospital Oestra, Goeteborg, Sweden
  • 13liaison person ARPES
Further Information

Publication History

Publication Date:
08 August 2002 (online)

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Zusammenfassung

Bei den vorliegenden Empfehlungen handelt es sich um die deutsche Übersetzung der vom Paediatric Committee der European Association of Nuclear Medicine (EANM) publizierten Guidelines.

Abstract

These “Empfehlungen” are the german translation of the Guidelines on MIBG-Scintigraphy in Children, which were published by the Paediatric Committee of the European Association of Nuclear Medicine.

Schlüsselwörter

MIBG-Szintigraphy - Leitlinie - Kinder

Key words

MIBG-scintigraphy - Guidelines - Children

Literatur

  • 1 Giammarile F, Boneu A , Edeline V, Lumbroso J, Siles S, Wioland M. Guide de realisation de la scintigraphie à la méta-iodobenzylguanidine (mIBG) en oncologie pédiatrique.  Med Nucl. 2000;  24 35-41
    PubMedSearch in Google Scholar
  • 2 Shapiro B, Copp J E, Sisson J  C, Eyre P L, Wallis J, Beierwaltes W H . Iodine-131 metaiodobenzylguanidine for the locating of suspected pheochromocytoma: experience in 400 cases.   J Nucl Med. 1985;  26 576-585
    PubMedSearch in Google Scholar
  • 3 Sisson J C, Shulkin B L. Nuclear medicine imaging of pheochromocytoma and neuroblastoma.  Q J Nucl Med. 1999;  43 217-223
    PubMedSearch in Google Scholar
  • 4 Leung A, Shapiro B, Hattner R, Kim E, de Kraker J, Ghazzar N, Hartmann O, Hoefnagel C A, Jamadar D A, Kloos R, Lizotte P, Lumbroso J, Rufini V, Shulkin B L, Sisson J C, Thein A, Troncone  L. Specificity of radioiodinated MIBG for neural crest tumors in childhood.  J Nucl Med. 1997;  38 1352-1357
    PubMedSearch in Google Scholar
  • 5 Khafagi  F A, Shapiro B, Fischer M, Sisson J C , Hutchinson R, Beierwaltes W H. Phaeochromocytoma and functioning paraganglioma in childhood and adolescence: role of iodine 131 metaiodobenzylguanidine.  Eur J Nucl Med. 1991;  18 191-198
    PubMedSearch in Google Scholar
  • 6 Shulkin  B L, Shapiro B. Current concepts on the diagnostic use of MIBG in children.   J Nucl Med. 1998;  39 679-688
    PubMedSearch in Google Scholar
  • 7 Wieland D M, Wu J, Brown L E, Mangner T J, Swanson D P, Beierwaltes W H . Radiolabeled adrenergi neuron-blocking agents: adrenomedullary imaging with [131I]iodobenzylguanidine.  J Nucl Med. 1980;  21 349-353
    PubMedSearch in Google Scholar
  • 8 Khafagi F A, Shapiro B, Gross M D. The adrenal gland. In: Maisey MN, Britton KE, Gilday DL (eds). Clinical Nuclear Medicine. Chapman & Hall, London 1989; 271-291
  • 9 Kinnier-Wilson  L M, Draper G J. Neuroblastoma, its natural history and prognosis: a study of 487 cases.  Br Med J. 1974;  3 301-307
    CrossrefPubMedSearch in Google Scholar
  • 10 Young J L, Ries L G, Silverberg E, Horm J W, Miller R W. Cancer incidence, survival, and mortality for children younger than age 15 years.  Cancer. 1986;  58 (Suppl 2) 598-602
    PubMedSearch in Google Scholar
  • 11 Jacobs A, Delree M, Desprechins B, Otten J, Ferster A , Jonckheer M H, Mertens J, Ham H R, Piepsz A. Consolidating the role of *I-MIBG-scintigraphy in childhood neuroblastoma: five years of clinical experience.  Pediatr Radiol. 1990;  20 157-159
    CrossrefPubMedSearch in Google Scholar
  • 12 Gelfand M J. Meta-iodobenzylguanidine in children.   Semin Nucl Med. 1993;  23 231-242
    CrossrefPubMedSearch in Google Scholar
  • 13 Lumbroso J D, Guermazi F, Hartmann O, Coornaert S, Rabarison Y, Leclere J G, Couanet D, Bayle C, Caillaud J M, Lemerle J. et al . Meta-iodobenzylguanidine (mIBG) scans in neuroblastoma: sensitivity and specificity, a review of 115 scans.  Prog Clin Biol Res. 1988;  271 689-705
    PubMedSearch in Google Scholar
  • 14 Parisi M T, Greene M K, Dykes T M, Moraldo T V, Sandler E D, Hattner R S. Efficacy of metaiodobenzylguanidine as a scintigraphic agent for the detection of neuroblastoma.  Invest Radiol. 1992;  27 768-773
    PubMedSearch in Google Scholar
  • 15 Moyes J, McCready V R, Fullbrook  A. Neuroblastoma MIBG in its diagnosis and management. Springer 1989
  • 16 Perel Y, Conway J, Kletzel M, Goldman J, Weiss S, Feyler A, Cohn S L. Clinical impact and prognostic value of metaiodobenzylguanidine imaging in children with metastatic neuroblastoma.  J Pediatr Hematol Oncol. 1999;  21 13-18
    CrossrefPubMedSearch in Google Scholar
  • 17 Hoefnagel C A, De Kraker J, Valdes Olmos R  A, Voute P A. [131I]MIBG as a first line treatment in advanced neuroblastoma.  Q J Nucl Med. 1995;  39 (Suppl 1) 61-64
    PubMedSearch in Google Scholar
  • 18 Lumbroso J, Hartmann O, Schlumberger  M. Therapeutic use of [131I]metaiodobenzylguanidine in neuroblastoma: a phase II study in 26 patients. „Societe Francaise d'Oncologie Pediatrique” and Nuclear Medicine Co-investigators.  J Nucl Biol Med. 1991;  35 220-223
    PubMedSearch in Google Scholar
  • 19 Mairs R J. Neuroblastoma therapy using radiolabelled [131I]meta- iodobenzylguanidine ([131I]MIBG) in combination with other agents.  Eur J Cancer. 1999;  35 1171-1173
    CrossrefPubMedSearch in Google Scholar
  • 20 Gordon I, Peters A M, Gutman A, Morony S, Dicks-Mireaux C, Pritchard J. Skeletal assessment in neuroblastoma - the pitfalls of iodine-123- MIBG scans.  J Nucl Med. 1990;  31 129-134
    PubMedSearch in Google Scholar
  • 21 Solanki K K, Bomanji J, Moyes J, Mather S J, Trainer P J, Britton K E. A pharmacological guide to medicines which interfere with the biodistribution of radiolabelled meta-iodobenzylguanidine (MIBG).  Nucl Med Commun. 1992;  13 513-521
    CrossrefPubMedSearch in Google Scholar
  • 22 Piepsz A, Hahn K, Roca I, Ciofetta G, Toth G, Gordon I, Kolinska J, Gwidlet J. A radiopharmaceuticals schedule for imaging in paediatrics. Paediatric Task Group European Association Nuclear Medicine.  Eur J Nucl Med. 1990;  17 127-129
    CrossrefPubMedSearch in Google Scholar
  • 23 Stabin M G, Gelfand M J. Dosimetry of pediatric nuclear medicine procedures.  Q J Nucl Med. 1998;  42 93-112
    PubMedSearch in Google Scholar
  • 24 Pintelon H, Jonckheer M H, Piepsz A. Paediatric nuclear medicine procedures: routine sedation or management of anxiety.  Nucl Med Commun. 1994;  15 664-666
    CrossrefPubMedSearch in Google Scholar
  • 25 Rufini V, Fisher G A, Shulkin B L, Sisson J C, Shapiro B. Iodine-123-MIBG imaging of neuroblastoma: utility of SPECT and delayed imaging.  J Nucl Med. 1996;  37 1464-1468
    PubMedSearch in Google Scholar
  • 26 Rufini V, Giordano A, Di Giuda D, Petrone A, Deb G, De Sio L, Donfrancesco A, Troncone L. [123I]MIBG scintigraphy in neuroblastoma: a comparison between planar and SPECT imaging.  Q J Nucl Med. 1995;  4 25-28
    PubMedSearch in Google Scholar
  • 27 Gelfand M J, Elgazzar A H, Kriss V M, Masters P R, Golsch G J. Iodine-123-MIBG SPECT versus planar imaging in children with neural crest tumors.  J Nucl Med. 1994;  35 1753-1757
    PubMedSearch in Google Scholar
  • 28 Nakajo M, Shapiro B, Copp J , Kalff V, Gross M D, Sisson J C, Beierwaltes W H. The normal and abnormal distribution of the adrenomedullary imaging agent m-[I-131]iodobenzylguanidine (I-131 MIBG) in man: evaluation by scintigraphy.  J Nucl Med. 1983;  24 672-682
    PubMedSearch in Google Scholar
  • 29 Bonnin F, Lumbroso J, Tenenbaum F, Hartmann O, Parmentier C. Refining interpretation of MIBG scans in children.  J Nucl Med. 1994;  35 803-810
    PubMedSearch in Google Scholar
  • 30 Lumbroso J, Giammarile F, Hartmann O, Bonnin F, Parmentier C. Upper clavicular and cardiac meta-[123I]iodobenzylguanidine uptake in children.  Q J Nucl Med. 1995;  39 17-20
    PubMedSearch in Google Scholar

Prof. Dr. med. K. Hahn

Klinik und Poliklinik für Nuklearmedizin

Ludwig-Maximilians-Universität München

Ziemssenstr. 1

80336 München

Phone: +49-89-61 60-24 42

Fax: +49-89-51 60-44 88

Email: hahn@nuk.med.uni-muenchen.de