Synthesis 2002(11): 1523-1529
DOI: 10.1055/s-2002-33332
PAPER
© Georg Thieme Verlag Stuttgart · New York

Hyrtiosanes from Labdanes: (-)-Hyrtiosal from Sclareol

Pilar Basabe*a, Alberto Diegoa, David Díeza, Isidro S. Marcosa, Faustino Mollinedob, Julio G. Uronesa
a Departimento de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain
Fax: +34(923)294574; e-Mail: pbb@usal.es;
b Centro de Investigación del Cáncer, CSIC-Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain
Weitere Informationen

Publikationsverlauf

Received 18 December 2001
Publikationsdatum:
23. August 2002 (online)

Abstract

(-)-Hyrtiosal and its C-16 epimer have been prepared from sclareol in moderate yield. The absolute configuration of na­tural product (-)-hyrtiosal has being determined.

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Crystallographic data (excluding structure factors) for the structures in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC 145607. Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44(0)1223336033; e-mail: deposit@ccdc.cam.ac.uk.