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Int J Sports Med 2002; 23(6): 433-438
DOI: 10.1055/s-2002-33740
Training & Testing
© Georg Thieme Verlag Stuttgart · New York

Time to Exhaustion at V˙O2max is Related to the Lactate Exchange and Removal Abilities

L.  Messonnier1, 2 , H.  Freund3 , C.  Denis4 , D.  Dormois4 , A.-B.  Dufour5 , J.-R.  Lacour2
  • 1Laboratoire de Modélisation des Activités Sportives, Département STAPS - UFR CISM - Université de Savoie, Campus Universitaire, Le Bourget du Lac Cedex, France
  • 2Laboratoire de Physiologie de I'Exercice, GIP Exercice - EA 645, Faculté de Médecine Lyon-Sud, Oullins Cedex, France
  • 3Laboratoire de Pharmacologie et de Physico-Chimie des Interactions Moléculaires et Cellulaires, Faculté de Pharmacie- UMR CNRS 7034, Illkirch Cedex, France
  • 4Laboratoire de Physiologie, GIP Exercice, CHU de Saint-Etienne,Hôpital de Saint Jean Bonnefonds, Saint-Etienne Cedex 2, France
  • 5Laboratoire de Biométrie et de Biologie Evolutive, UMR-CNRS 5558, Université Claude Bernard - Lyon 1, Villeurbanne Cedex, France
Further Information

Publication History

Accepted after revision: November 15, 2001

Publication Date:
05 September 2002 (online)

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Abstract

The aim of the present study was to investigate the relationships between lactate exchange and removal abilities and the capacity to prolong exercise, as assessed by the time to exhaustion (Tlim) at a work rate corresponding to V˙O2max (Pamax). The individual blood lactate recovery curves obtained for 13 untrained subjects after 5 min 90 % Pamax exercise were fitted to the biexponential time function: La(t) = La(0) + A1(1-e-γ1 × t) + A2(1-e-γ2 × t), where t is time into the recovery, La(0) is the arterialized lactate concentration measured at the end of the exercise, γ1 and γ2 are velocity constants denoting the lactate exchange and removal abilities, respectively. Tlim was positively related to γ1 and γ2 (r = 0.60, p < 0.05 and r = 0.56, p < 0.05, respectively) but was negatively related to La(0) (r = 0.75, p < 0.01). γ1 was positively related to the capillary density (r = 0.69, p < 0.01) and to the number of capillaries per type I fiber area (r = 0.62, p < 0.05). It was concluded that 1) high lactate exchange and removal abilities would allow continuing a high-intensity exercise for a longer duration, and 2) a high capillary density may explain the associated high lactate exchange ability.

Key words

Exercise tolerance - fatigue - lactate kinetic - recovery

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J.-R. Lacour

Laboratoire de Physiologie de I'Exercice, GIP Exercice · EA 645, Faculté de Médecine Lyon-Sud

BP 12 · 69921 Oullins Cedex · France ·

Phone: +33 (4) 78863135

Fax: +33 (4) 78863135

Email: lacour@univ-lyon1.fr