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DOI: 10.1055/s-2002-33872
VEGF-C, VEGF-D und VEGF-Rezeptor 3: neue Schlüsselfaktoren der Lymphangiogenese und Tumormetastasierung
VEGF-C, VEGF-D and VEGF-Receptor 3: Novel Key Regulators of Lymphangiogenesis and Cancer MetastasisPublication History
Publication Date:
05 September 2002 (online)
Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, Riccardi L, Alitalo K, Claffey K, Detmar M. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 2001; 7: 192-198
Mandriota SJ, Jussila L, Jeltsch M, Compagni A, Baetens D, Prevo R, Banerji S, Huarte J, Montesano R, Jackson DG, Orci L, Alitalo K, Christofori G, Pepper MS. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J 2001; 20: 672-682
Stacker SA, Caesar C, Baldwin ME, Thornton GE, Williams RA, Prevo R, Jackson DG, Nishikawa S, Kubo H, Achen MG. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 2001; 7: 186-191
Makinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, Kauppinen R, Jackson DG, Kubo H, Nishikawa S, Yla-Herttuala S, Alitalo K. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med 2001; 7: 199-205
Priv.-Doz. Dr. med. Michael Höcker
Medizinische Klinik mit Schwerpunkt Hepatologie,
Gastroenterologie, Endokrinologie und Stoffwechsel, Universitätsklinikum
Charité, Campus Virchow-Klinikum, Humboldt Universität
Berlin
Augustenburger Platz 1
13353 Berlin
Email: hoecker@charite.de