Zusammenfassung
Die Wächterlymphknotenbiopsie wird weltweit als grundsätzliche Methode des nodalen
Stagings bei Melanom angesehen. Inzwischen wird allgemein akzeptiert, dass ein positiver
Wächterlymphknotenbefund der wichtigste prognostische Faktor für das Gesamtüberleben
darstellt. Die entscheidende Frage dieser Methode ist jedoch, ob das diagnostische
Verfahren Wächterlymphknotenbiopsie gefolgt ist von einem therapeutischen Nutzen für
die Patienten. Diese Frage wird zur Zeit in verschiedenen Studienkonzepten der USA
und Deutschlands überprüft.
Abstract
Sentinel lymph node biopsy is regarded world-wide as the principal staging method
for melanoma. Meanwhile it is commonly accepted that a positive sentinel lymph node
is the most important prognostic factor for overall survival. The crucial question
for this method, however, is whether the diagnostic procedure sentinel lymph node
biopsy is followed by a therapeutical benefit for the patients. These questions are
at present answered in randomized multicentre clinical trials in the USA and Germany.
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Prof. Dr. med. R. Stadler
Hautklinik am Klinikum Minden
Portastraße 7-9 · 32423 Minden ·
eMail: hautklinik@klinikum-minden.de
