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Aktuelle Dermatologie 2002; 28(8/9): 314-318
DOI: 10.1055/s-2002-33967
Tumormarker
© Georg Thieme Verlag Stuttgart · New York

Prognoseevaluation mittels Immunhistologie

Immunohistology for Prognostic EvaluationJ.  Kamarashev1 , G.  Burg1 , W.  Kempf1 , R.  Dummer1
  • 1Dermatologische Klinik, Universitäts-Spital Zürich
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Publication History

Publication Date:
10 September 2002 (online)

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Zusammenfassung

Die Tumordicke ist der wichtigste prognostische Parameter für kutane Melanome. Jedoch wäre es wünschenswert mit zusätzlichen Untersuchungen die Prognose des individuellen Patienten weiter abzusichern. Bewährt haben sich in diesem Zusammenhang in mehreren Studien Proliferationsmarker und auch Adhäsionsmoleküle sowie immunologisch relevante Moleküle wie TAP1, das in der Antigenverarbeitung benötigt wird.

Abstract

The tumor thickness is the most important prognostic parameter for cutaneous melanoma. However, additional examinations are desirable to predict the prognosis of the individual patient. In this context, proliferation markers and also adhesion molecules as well as immunological relevant molecules such as TAP1, which is involved in antigen processing, have been shown to be of prognostic relevance.

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Prof. Dr. med. Reinhard Dummer

Dermatologische Klinik · Universitäts-Spital Zürich

Gloriastraße 31 · 8091 Zürich · Schweiz

Email: reinhard.dummer@der.usz.ch