Three sesquiterpene lactones were isolated from Lourteigia ballotaefolia (H. B. K.). 9β-hydroxy-atripliciolide-8-O-tiglate (1) was isolated for the first time from this plant and was previously reported in Conocliniopsis prasiifolia (DC) K. et R., 9β-hydroxy-atripliciolide-8-O-(5′-acetoxytiglate) (2) had been already reported in this species. The minor component, 9β-(tigloyloxy)-atripliciolide, is a new compound. The anti-inflammatory activity of compounds 1 and 2 was evaluated using the croton oil ear test in mice.
References
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Sosa S, Tubaro A, Kastner U, Glasl S, Jurenitsch J, Della Loggia R.
Topical anti-inflammatory activity of a new germacrane derivative from Achillea pannonica
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Planta Med.
2001;
67
654-8
