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DOI: 10.1055/s-2002-34412
© Georg Thieme Verlag Stuttgart · New York
Quinoline Alkaloids and Anti-Platelet Aggregation Constituents from the Leaves of Melicope semecarpifolia
Publication History
Received: January 4, 2002
Accepted: April 21, 2002
Publication Date:
30 September 2002 (online)
![](https://www.thieme-connect.de/media/plantamedica/200209/lookinside/thumbnails/10.1055-s-2002-34412-1.jpg)
Abstract
Three new quinoline alkaloids, melisemine, confusadine, and melicarpinone, together with twelve known compounds have been isolated from the leaves of Melicope semecarpifolia. The structures of these three compounds were determined through spectral analyses. Confusadine was demonstrated to be an anti-platelet aggregation constituent.
Key words
Melicope semecarpifolia - Rutaceae - leaves - alkaloids - quinoline - 2-quinolone - melisemine - furoquinolines - confusadine - melicarpinone - anti-platelet aggregation activity
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Prof. Dr. I. S. Chen
Graduate Institute of Pharmaceutical Sciences
Kaohsiung Medical University
Kaohsiung, Taiwan
Republic of China
Email: m635013@cc.kmu.edu.tw
Fax: +886-7-3210683