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Synthesis 2002(16): 2431-2439
DOI: 10.1055/s-2002-35215
DOI: 10.1055/s-2002-35215
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Quaternary Alkylammonium Sulfobetaines
Further Information
Received
11 August 2002
Publication Date:
04 November 2002 (online)
Publication History
Publication Date:
04 November 2002 (online)
Abstract
A series of quaternary alkylammonium sulfobetaines of general formula RN+(CH3)2(CH2)nSO3 -, where n = 2-4, have been synthesised by reacting the corresponding N,N-dimethylamines with either sodium 2-chloroethanesulfonate (n = 2), 1,3-propanesultone (n = 3), or 1,4-butanesultone (n = 4). Full details of the preparation of the required N,N-dimethylamines are reported.
Key words
Mannich bases - Friedel-Crafts reactions - zwitterions - sultones - surfactants
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