Synthesis 2002(16): 2431-2439
DOI: 10.1055/s-2002-35215
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Quaternary Alkylammonium Sulfobetaines

Robert S. Ward*a, Joanna Daviesa, Geoffrey Hodgesb, David W. Robertsc
a Department of Chemistry, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
Fax: +44(1792)295747; e-Mail: r.s.ward@swansea.ac.uk;
b Unilever Research Colworth Laboratory, Sharnbrook, Bedford MK44 1LQ, UK
c Unilever Research and Development Port Sunlight, Quarry Road East, Bebington, Wirral CH63 3JW, UK
Further Information

Publication History

Received 11 August 2002
Publication Date:
04 November 2002 (online)

Abstract

A series of quaternary alkylammonium sulfobetaines of general formula RN+(CH3)2(CH2)nSO3 -, where n = 2-4, have been synthesised by reacting the corresponding N,N-dimethylamines with either sodium 2-chloroethanesulfonate (n = 2), 1,3-propanesultone (n = 3), or 1,4-butanesultone (n = 4). Full details of the preparation of the required N,N-dimethylamines are reported.

1

Roberts, D. W.; Costello, J. unpublished results.