An Expeditious One-Pot Synthesis of Thiiranes from α-Halo Ketones in Solvent­-Free Conditions Using Microwaves

Lal Dhar S.  Yadav; Ritu  Kapoor

doi:10.1055/s-2002-35222

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Synthesis 2002(16): 2344-2346
DOI: 10.1055/s-2002-35222

SHORTPAPER

An Expeditious One-Pot Synthesis of Thiiranes from α-Halo Ketones in Solvent-Free Conditions Using Microwaves

Lal Dhar S. Yadav*, Ritu Kapoor
Department of Chemistry, University of Allahabad, Allahabad 211 002, India
Fax: +91(532)545021; e-Mail: lds-yadav@hclinfinet.com;

Further Information

Publication History

Received 19 July 2002
Publication Date:
04 November 2002 (online)

Abstract
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Abstract

Thiiranes are obtained in excellent yields and with high diastereoselectivity upon microwave irradiation of a mixture of α-haloketones, O,O-diethyl hydrogen phosphorodithioate and alumina-supported sodium borohydride in solvent-free conditions.

Key words

α-haloketones - thiiranes - stereoselective synthesis - microwaves - solvent free - alumina supported

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