Abstract
Two new triterpenoids, guajavolide (2α,3β,6β,23-tetrahydroxyurs-12-en-28,20β-olide; 1) and guavenoic acid (2α,3β,6β,23-tetrahydroxyurs-12,20(30)-dien-28-oic acid; 2) along with one known triterpene oleanolic acid (3) were isolated from the fresh leaves of Psidium guajava. Their structure elucidation and stereochemistry were determined by spectroscopic experiments, including 2D-NMR techniques.
References
-
1
Ali M A, Shamsuzzaman M.
Isolation and characterization of antibacterial constituents from the bark of Psidium guajava
.
Bangladesh Journal of Scientific and Industrial Research.
1996;
31
133-9
-
2
El-Badrawy E EY.
Hypoglycemic effect of the glycan isolated from guava fruit (Psidium guajava).
VDLUFA-Schriftenr.
1999;
52
203-6
-
3
Olajide O A, Awe S O, Makinde J M.
Pharmacological studies on the leaf of Psidium guajava
.
Fitoterapia.
1999;
70
25-31
-
4
Sahu N P, Roy S K, Mahato S B.
Spectroscopic determination of structures of triterpenoid trisaccharides from Centella asiatica
.
Phytochemistry.
1989;
28
2852-4
-
5
Adnyana I K, Tezuka Y, Banskota A H, Tran K Q, Kadota S.
Three new triterpenes from the seeds of Combretum quadrangulare and their hepatoprotective activity.
Journal of Natural Products.
2001;
64
360-3
-
6
Ouyang M, Yang C, Chen Z, Wang H.
Triterpenes and Triterpenoid glycosides from the leaves of Ilex kudincha
.
Phytochemistry.
1996;
41
871-7
-
7
Sanoko R, Speranza G, Pizza C, De Tommasi N.
Triterpene saponins from Alternanthera repens
.
Phytochemistry.
1999;
51
1043-7
-
8
Siddiqui S, Siddiqui B S, Naeed A, Begum S.
New pentacyclic triterpenoids from Plumeria obtusa
.
Pakistan Journal of Scientific and Industrial Research.
1989;
32
781-4
-
9 Chapman & Hall/CRC Chemical Dictionaries on CD-ROM, Chapman & Hall/CRC, 1982 - 2002.
-
10 Ahmad V U, Atta-ur-Rahman . Handbook of Natural Products Data. Pentacyclic Triterpenoids. Vol. 2 New York; Elsevier 1994: 111-2 and the references cited therein
Dr. Sabira Begum
H.E.J. Research Institute of Chemistry
International Centre for Chemical Sciences
University of Karachi
Karachi-75270
Pakistan
Phone: +(92-21) 9243233, 9243237-8
Fax: +(92-21) 9243190-1
Email: sabira@khi.comsats.net.pk