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Synthesis 2003(1): 0019-0020
DOI: 10.1055/s-2003-36252
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

A Direct Introduction of the Mercaptoacetic Acid Unit into Amino Acid Esters

George A. Kraus*, Jaehoon Bae, Prabir K. Choudhury
Department of Chemistry, Iowa State University, Ames, IA 50011, USA
Fax: +1(515)2940105; e-Mail: gakraus@iastate.edu;
Further Information

Publication History

Received 1 August 2002
Publication Date:
18 December 2002 (online)

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Abstract

The reaction of amino acid esters with 1,3-oxathiolan-5-one 1a provided thiol amides 3.

Key words

combinatorial chemistry - amino acids - amines - ligands - thiols - acylations - esters

    References

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