RSS-Feed abonnieren
DOI: 10.1055/s-2003-37747
Die elektrophysiologische Untersuchung des Masseterreflexes
Ableittechnik, klinischer Einsatz und topodiagnostische BedeutungElectrophysiological Examination of the Masseter ReflexTechnique, Clinical Application and Topodiagnostic Significance Für Herrn Prof. Dr. H. C. Hopf, der mir (neben vielen anderen Dingen) auch den Masseterreflex gezeigt hatPublikationsverlauf
Publikationsdatum:
10. März 2003 (online)
Zusammenfassung
Der Masseterreflex ist ein monosynaptischer Muskeldehnungsreflex, dessen zentraler Reflexbogenanteil im Hirnstamm zwischen dem Niveau des Okulomotoriuskerns und der Nerveneintrittszone des N. trigeminus im mittleren Pons verläuft. Hier ergeben sich enge anatomische Beziehungen zu Abschnitten der intramesenzephalen Nn. oculomotorius und trochlearis, der intrapontinen Nn. abducens, facialis und vestibularis sowie zum Fasciculus longitudinalis medialis. Die vorliegende Arbeit beschreibt die Technik der elektrophysiologischen Untersuchung des Masseterreflexes, die klinischen Anwendungsbereiche und die topodiagnostische Bedeutung.
Abstract
The myotactic masseter reflex is monosynaptically transmitted. The central reflex loop closely follows the entire length of the trigeminal mesencephalic tract and nucleus between the 3rd nerve nucleus and the 5th nerve motor nucleus levels. It is adjacent to the proximal segment of the intramesencephalic 3rd nerve, the intramesencephalic 4th nerve, the proximal intrapontine segment of the 6th nerve, the intrapontine segment of the 7th nerve near the 6th nerve nucleus, the intrapontine segment of the vestibular nerve in the vicinity of the vestibular nuclei, and the medial longitudinal fasciculus. The present paper reviews the technique of electrophysiological masseter reflex testing, its clinical applications and its topodiagnostic significance.
Key words
Masseter reflex - brainstem infarction - multiple sclerosis brainstem lesion - MRI
Literatur
- 1 Cody F WJ, Lee R WH, Taylor A. A functional analysis of the components of the mesencephalic nucleus of the fifth nerve in the cat. J Physiol. 1972; 226 249-261
- 2 Capra N F, Anderson K V, Atkinson R C. Localization and morphometric analysis of masticatory muscle afferent neurons in the nucleus of the mesencephalic root of the trigeminal nerve in the cat. Acta Anat. 1985; 122 115-125
- 3 Nozaki S, Iriki A, Nakamura Y. Trigeminal mesencephalic neurons innervating functionally identified muscle spindles and involved in the monosynaptic stretch reflex of the lateral pterygoid muscle of the guinea pig. J Comp Neurol. 1985; 236 106-120
- 4 Kubota K, Narita N, Ohkubo K, Hosaka K, Nagae K, Lee M S, Kawamoto T, Kubota M, Odagiri N. Central projections of proprioceptive afferents arising from maxillo-facial regions in some animals studied by HRP-labelling technique. Anat Anz. 1988; 165 229-251
- 5 Chen K, Wen C, Shieh J. HRP-labelled masticatory neurons in the rat trigeminal mesencephalic nucleus: a light and electron microscopic study. Proc Natl Sci Council Repub China B. 1989; 13 298-306
- 6 Szentagothai J. Anatomical considerations of monosynaptic reflex arcs. J Neurophysiol. 1948; 11 445-454
- 7 Mc Intyre A K, Robinson R G. Pathway for the jaw-jerk in man. Brain. 1959; 82 468-474
- 8 Hosokawa H. Proprioceptive innervation of striated muscle in the territory of the cranial nerves. Texas Rep Biol Med. 1961; 19 405-446
- 9 Gudmundsson K, Rhoton A L, Rushton J G. Detailed anatomy of the intracranial portion of the trigeminal nerve. J Neurosurg. 1971; 35 592-600
- 10 Goor C, Ongerboer de Visser B W. Jaw and blink reflexes in trigeminal nerve lesions. Neurology. 1976; 26 95-97
- 11 Ferguson I T. Electrical study of jaw and orbicularis oculi reflexes after trigeminal nerve surgery. J Neurol Neurosurg Psychiatry. 1978; 41 819-823
- 12 Jaquin M F, Rhoades R W, Entiejian H L, Egger M D. Organization and morphology of masticatory neurons in the rat: a retrograde HRP study. J Comp Neurol. 1983; 218 239-256
- 13 Rokx J TM, van Willigen J D, Jansen H WB. Muscle fiber types and muscle spindles in the jaw musculature of the rat. Arch Oral Biol. 1984; 29 25-31
- 14 Rokx J TM, van Willigen J D, Juch P JW. Distribution of innervating neurons of masticatory muscle spindles in the rat: a HRP study. Exp Neurol. 1985; 88 562-569
- 15 Appenteng K, Donga R, Williams R G. Morphological and electrophysiological determinations of the projections of the jaw-elevator muscle spindle afferents in rats. J Physiol. 1985; 369 93-113
- 16 Nomura S, Mizuno N. Differential distribution of cell bodies and central axons of mesencephalic trigeminal nucleus neurons supplying the jaw-closing muscles and periodontal tissue. Brain Res. 1985; 359 311-319
- 17 Appenteng K, O'Donovan M J, Somjen G, Stefens G A, Taylor A. The projection of jaw elevator muscle spindle afferents to fifth nerve motoneurons in the cat. J Neurophysiol. 1978; 279 409-423
- 18 Nieuwenhuys R, Voogd J, van Huijzen C. The human central nervous system, 3rd ed. Berlin; Springer 1989
- 19 Hassler O. Arterial pattern of human brainstem. Normal appearance and deformation in expanding supratentorial conditions. Neurology. 1967; 17 368-375
- 20 Duvernoy A M. Human brainstem vessels. Berlin; Springer 1978
-
21 Miller N R.
The vertebrobasilar arterial system and its branches. In: Miller NR Walsh and Hoyt's Clinical Neuro-Ophthalmolgy. Baltimore; Williams & Wilkins 1991 Vol 4: 1904-1935 - 22 Goodwill C J. The normal jaw reflex: measurement of the action potential in the masseter muscles. Ann Phys Med. 1968; 9 183-188
- 23 Kimura J, Rodnitzky R L, Van Allen M W. Electrodiagnostic study of trigeminal nerve. Orbicularis oculi reflex and masseter reflex in trigeminal neuralgia, partrigeminal syndrome, and other lesions of the trigeminal nerve. Neurology. 1970; 20 574-583
- 24 Ongerboer de Visser B W, Goor C. Electromyographic and reflex study in idiopathic and symptomatic trigeminal neuralgias: latency of the jaw and blink reflexes. J Neurol Neurosurg Psychiatry. 1974; 37 1225-1230
- 25 Ongerboer de Visser B W, Goor C. Jaw reflexes and masseter electromyograms in mesencephalic and pontine lesions. J Neurol Neurosurg Psychiatry. 1976; 39 90-92
- 26 Ongerboer de Visser B W. Afferent limb of the human jaw reflex: electrophysiologic and anatomic study. Neurology. 1982; 32 563-566
- 27 Sanders E ACM, Ongerboer de Visser B W, Barendswaard E C. Jaw, blink and corneal reflex latencies in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1985; 48 1284-1289
-
28 Görömbey Z, Csecsei G, Klug N.
Veränderungen des Masseter-Reflexes bei primären und sekundären Hirnstammschädigungen. In: Lowitzsch K (Hrsg) Hirnstammreflexe. Methodik und klinische Anwendung. Stuttgart; Thieme 1986: 204-210 -
29 Lowitzsch K, Marzi I.
Multimodale Hirnstammreflexe in der Prognose des Koma. In: Lowitzsch K (Hrsg) Hirnstammreflexe. Methodik und klinische Anwendung. Stuttgart; Thieme 1986: 237-251 - 30 Hopf H C, Gutmann L. Diabetic 3rd nerve palsy: evidence for a mesencephalic lesion. Neurology. 1990; 40 1041-1045
- 31 Bremer T. Der Eigenreflex des Musculus masseter: Erstellung der Normwerttabelle. Mainz; Thesis 1993
- 32 Fitzek S, Fitzek C, Hopf H C. The masseter reflex: postprocessing methods and influence of age and gender. Eur Neurol. 2001; 46 202-205
- 33 Yates S K, Brown W F. The human jaw jerk: Electrophysiologic methods to measure latency, normal values and changes in multiple sclerosis. Neurology. 1981; 31 632-634
- 34 Cruccu G, Inghileri M, Fraioli B, Guidetti B, Manfredi M. Neurophysiologic assessment of trigeminal function after surgery for trigeminal neuralgia. Neurology. 1987; 37 631-638
- 35 Krämer G, Bremer T, Hubrich P, Lüder G, Hopf H C. Altersabhängige Normwerte des Masseter Reflexes. Akt Neurol. 1992; 19; Suppl XVIII
- 36 Ben Ghezala K, Hundemer H P, Koehler J, Urban P P, Connemann B, Hopf H C. The variance of masseter reflex (MassR) latencies and amplitudes with different recording techniques and follow-up with weekly intervals. Electroencephal clin Neurophysiol. 1996; 99 334
- 37 Hopf H C, Hinrichs C, Stoeter P, Urban P P, Marx J, Thömke F. Masseter reflex latencies and amplitudes are not influenced by supratentorial and cerebellar lesions. Muscle Nerve. 2000; 23 86-89
-
38 Hopf H C, Thömke F, Tettenborn B.
The masseter myotactic reflex in the diagnosis of brainstem lesions. In: Valls-Solé Tolosa E (eds) Brainstem Reflexes and Functions. Madrid; ENE Publicidad, S.A 1998: 143-152 - 39 Mika-Grüttner A, Marx J, Thömke F, Fitzek S, Fitzek C, Urban P P, Stoeter P, Hopf H C. Wertigkeit der Elektrophysiologie bei Hirnstammischämien und normaler diffusionsgewichteter und hochauflösender MRT. Klin Neurophysiol. 2001; 32 135-140
- 40 Marx J J, Mika-Grüttner A, Thömke F, Fitzek S, Fitzek C, Vucurevic G, Urban P P, Stoeter P, Hopf H C. Electrophysiological brainstem testing in the diagnosis of reversible brainstem ischemia. J Neurol. 2002; 249 1041-1047
- 41 Hundemer H P. Der Masseterreflex in der Diagnostik der Multiplen Sklerose. Ein Vergleich mit anderen elektrophysiologischen Methoden und mit der Kernspintomographie des Gehirns. Mainz; Thesis 1997
- 42 Hopf H C, Thömke F, Gutmann L. Mid brain versus pontine medial longitudinal fasciculus lesions. The utilization of masseter and blink reflexes. Muscle Nerve. 1991; 14 326-330
- 43 Thömke F, Hopf H C. Höhenlokalisation von Läsionen bei internukleärer Ophthalmoplegie mittels Masseter- und Blinkreflex. Schweiz Rundschau Med (PRAXIS). 1992; 81 1481-1484
- 44 Thömke F, Tettenborn B, Hopf H C. Third nerve palsy as the sole manifestation of midbrain ischemia. Neuro-ophthalmology. 1995; 15 327-335
- 45 Thömke F. Isolated abducens palsies due to pontine lesions. Neuro-ophthalmology. 1998; 20 91-100
- 46 Thömke F, Hopf H C. Pontine lesions mimicking acute peripheral vestibulopathy. J Neurol Neurosurg Psychiatry. 1999; 66 340-349
- 47 Thömke F, Hopf H C. Isolated superior oblique palsies with electrophysiologically documented brainstem lesions. Muscle Nerve. 2000; 23 267-270
- 48 Thömke F, Urban P P, Marx J J, Mika-Grüttner A, Hopf H C. Seventh nerve palsies may be the only clinical sign of small pontine infarctions in diabetic and hypertensive patients. J Neurol. 2002; 249 1556-1562
- 49 Koehler J, Schwarz M, Urban P P, Voth D, Hölker C, Hopf H C. Masseter reflex and blink reflex abnormalitis in Chiari II malformation. Muscle Nerve. 2001; 24 425-427
- 50 Thömke F. Isolated cranial nerve palsies due to brainstem lesions. Muscle Nerve. 1999; 22 1168-1176
- 51 Thömke F, Gutmann L, Stoeter P, Hopf H C. Cerebrovascular brainstem diseases with isolated cranial nerve palsies. Cerebrovasc Dis. 2002; 13 147-155
- 52 Mika-Grüttner A, Thömke F, Marx J J, Urban P P, Ringel K, Hopf H C. Magnetic resonance imaging versus electrophysiological testing in internuclear ophthalmoplegia. Mov Disord. 2002; 17, Suppl 2 S92
Prof. Dr. med. Frank Thömke
Klinik und Poliklinik für Neurologie der Johannes Gutenberg-Universität Mainz
Langenbeckstraße 1
55101 Mainz
eMail: thoemke@neurologie.klinik.uni-mainz.de