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Semin Thromb Hemost 2003; 29(1): 043-048
DOI: 10.1055/s-2003-37970
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Radiological Evaluation of Hemophilic Arthropathy

Ray F. Kilcoyne1 , Rachelle Nuss2
  • 1Professor Emeritus, Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado
  • 2Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado
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Publication History

Publication Date:
17 March 2003 (online)

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ABSTRACT

Hemophilia leads to recurrent bleeding episodes in joints resulting in a severe destructive arthropathy in many cases. Staging of hemophilic joint disease is important for identifying the site of bleeding and planning appropriate therapy. However, classification systems based on plain X-ray findings have been insensitive at detecting the earlier, possibly reversible, changes of synovial hyperplasia. They may also underestimate the severity of cartilage damage. Magnetic resonance imaging (MRI) has been shown to more accurately assess a hemophilic joint. Tentative hemophilic arthropathy scales based on MRI findings are being developed. Hopefully, use of these scales will result in more consistent assessment of hemophilic joints and facilitate development of more targeted treatment and thus prevent or delay the later, destructive changes in the articular cartilage and bone.

KEYWORD

Hemophilia - MRI - synovitis - classification systems - joint disease