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Synlett 2003(5): 0702-0704
DOI: 10.1055/s-2003-38379
DOI: 10.1055/s-2003-38379
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York
Environmentally-Friendly Wohl-Ziegler Bromination: Ionic-Liquid Reaction and Solvent-Free Reaction
Further Information
Received
28 December 2002
Publication Date:
28 March 2003 (online)
Publication History
Publication Date:
28 March 2003 (online)
Abstract
Environmentally-friendly Wohl-Ziegler bromination of benzylic methyl groups was successfully carried out in ionic-liquid and solvent-free systems, to produce the corresponding benzylic bromides in good to moderate yields.
Key words
Wohl-Ziegler bromination - benzylic bromide - N-bromosuccinimide (NBS) - 2,2′-azobis(isobutyronitrile) (AIBN) - benzoyl peroxide - ionic-liquid - solvent-free
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