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Synthesis 2003(6): 0823-0828
DOI: 10.1055/s-2003-38677
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Facile and Selective Synthetic Method for the Preparation of Aromatic Dialdehydes from Diesters­ via the Amine-Modified SMEAH Reduction System

Kazutake Hagiya*, Sunao Mitsui, Hiroaki Taguchi
Chemical Research Laboratory, Toyo Kasei Kogyo Co., Ltd., 2900 Sone, Takasago, Hyogo 676-0082, Japan
Fax: +81(794)477180; e-Mail: kazutake-hagiya@toyokasei-kogyo.co.jp;
Further Information

Publication History

Received 21 October 2002
Publication Date:
16 April 2003 (online)

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Abstract

A new reduction system employing N-methylpiperazine-modified sodium bis(2-methoxyethoxy)aluminum hydride (NMP-SMEAH) for the conversion of aromatic diesters to dialdehydes is described. The method is plain and efficient, and can be carried out under mild and operationally simple conditions applicable for large scale productions.

Key words

aldehydes - amines - esters - hydrides - reductions

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