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Synthesis 2003(6): 0899-0905
DOI: 10.1055/s-2003-38681
DOI: 10.1055/s-2003-38681
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York
Synthesis of New 1,2,4- and 1,3,4-Oxadiazole Derivatives
Weitere Informationen
Received
9 December 2002
Publikationsdatum:
16. April 2003 (online)
Publikationsverlauf
Publikationsdatum:
16. April 2003 (online)
![](https://www.thieme-connect.de/media/synthesis/200306/lookinside/thumbnails/10.1055-s-2003-38681-1.jpg)
Abstract
A novel series of compounds structurally related to nonpeptide angiotensin II (AII) receptor antagonists has been prepared. In these compounds, the ‘spacer’ phenyl ring commonly found in almost all AII receptor antagonists was replaced by 1,2,4- and 1,3,4-oxadiazole rings.
Key words
hypertension - heterocycles - drugs - quinolines - antagonists - oxadiazoles
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