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DOI: 10.1055/s-2003-38880
Anti-Inflammatory and Analgesic Effects of a Mixture of Fatty Acids Isolated and Purified from Sugar Cane Wax Oil
Publication History
Received: August 28, 2002
Accepted: December 2, 2002
Publication Date:
23 April 2003 (online)
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Abstract
The anti-inflammatory and analgesic effects of FAM, a defined mixture of fatty acids isolated from sugar cane (Saccharum officinarum L.), was evaluated. Oral administration of this mixture showed anti-inflammatory activity in the cotton pellet granuloma assay and in the carrageenin-induced pleurisy test, both in rats, as well as in the peritoneal capillary permeability test in mice. In addition, FAM showed analgesic properties in the hot-plate model and in the acetic acid-induced writhings test, both in mice. In conclusion, these results provide evidence on the potential usefulness of the mixture of fatty acids from sugar cane wax oil in inflammatory disorders.
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Dra. Naris Ledon
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