Literatur
-
1
Wanebo H J, Vezeridis M P.
Pancreatic carcinoma in perspective. A continuing challenge.
Cancer.
1996;
78
(Suppl 3)
580-591
-
2
Burris H A. et al .
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
J Clin Oncol.
1997;
15
(6)
2403-2413
-
3
Bruns C A, Harbison M T, Kuniyasu H, Eue I, Fidler I J.
In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice.
Neoplasia.
1999;
1
50-62
-
4
Yamanaka Y. et al .
Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness.
Anticancer Res.
1993;
13
(3)
565-569
-
5
Mendelsohn J.
Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.
Clin Cancer Res.
1997;
3
2703-2707
-
6
Baselga I, Norton L, Masui H, Pandiella A, Copian K, Miller W H, Mendelsohn J.
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies.
J Natl Cancer Inst.
1993;
85
(16)
1327-1333
-
7
Gerber H P, McMurtrey A, Kowalski J, Yan M, Keyt B A, Dixit V, Ferrara N.
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation.
J Biol Chem.
1998;
273
30336-30343
-
8
Witte L, Hicklin D A, Zhu Z, Pytowski B, Kotanides H, Rockwell P, Bohlen P.
Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy.
Cancer Metastasis Rev.
1998;
17
155-161
-
9 Gorman C. The Hope & the Hype. Time, The Weekly Newsmagazine May 18 1998: 38-44
-
10
Guba M, Breitenbuch P von, Steinbauer M, Koehl G, Flegel S, Hornung W, Bruns C A, Zuelke C, Farkas S, Anthuber M, Jauch K K, Geissler E X.
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor.
Nat Med.
2002;
8
128-135
Dr. med. C. J. Bruns
Chirurgische Klinik u. Poliklinik Großhadern LMU München<
Marchioninistr. 15
81377 München