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Synthesis 2003(14): 2173-2178  
DOI: 10.1055/s-2003-41078
PAPER
© Georg Thieme Verlag Stuttgart · New York

An Efficient Route to Aliphatic 2,2-Dichloroaldehydes via Chlorination of Aldehydes or Alcohols with the System Cl2/Quaternary Ammonium Chloride

Franco Bellesiaa, Laurent De Buyck*b, Franco Ghelfi*a, Ugo M. Pagnonia, Andrew F. Parsonsc, Adriano Pinettia
a Dipartimento di Chimica, Università degli Studi di Modena e Reggio Emilia, via Campi 183, 41100 Modena, Italy
Fax: +39(59)373543; e-Mail: ghelfi.franco@unimo.it.;
b Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, University of Gent, Coupure Links 653, 9000 Gent, Belgium
c Department of Chemistry, University of York, Heslington, York YO10 5DD, UK
Further Information

Publication History

Received 30 April 2003
Publication Date:
24 September 2003 (online)

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Abstract

An effective and low waste method for preparing aliphatic 2,2-dichloroaldehydes has been achieved by halogenation of aldehydes or alcohols with Cl2, using tetraalkylammonium chlorides as recoverable catalysts.

Key words

alcohols - aldehydes - halogen - halogenation - halide

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