Parallel Synthesis of New β-Amino Esters via Conjugate Nucleophilic Additions­

Jacques Huck; Christiane Duru; Marie Louise Roumestant; Jean Martinez

doi:10.1055/s-2003-42084

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Parallel Synthesis of New β [2] -Amino Esters via Conjugate Nucleophilic Additions

Jacques Huck, Christiane Duru, Marie Louise Roumestant*, Jean Martinez
Laboratoire des Amino acides, Peptides et Protéines, UMR-CNRS 5810, Universités Montpellier I & II, 2 Place E. Bataillon, 34095 Montpellier Cedex 05, France
e-Mail: malou.roumestant@wanadoo.fr;

Abstract

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Abstract

The Michael addition of secondary cyclic aromatic and nonaromatic amines to methyl 2-{[(tert-butoxycarbonyl)amino]methyl}acrylate afforded substituted β [2] -amino esters in good to excellent yields.

Key words

addition reactions - eliminations - amines - heterocycles - esters

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References

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Parallel Synthesis of New β [2] -Amino Esters via Conjugate Nucleophilic Additions­

Parallel Synthesis of New β [2] -Amino Esters via Conjugate Nucleophilic Additions