Synthesis and Utility of α-Methoxy Phosphonates with a 1,3,2-Dioxaphosphorinane Ring

Manab Chakravarty; B. Srinivas; C. Muthiah; K. C. Kumara Swamy

doi:10.1055/s-2003-42395

PAPER

Synthesis and Utility of α-Methoxy Phosphonates with a 1,3,2-Dioxaphosphorinane Ring

Manab Chakravarty, B. Srinivas, C. Muthiah, K. C. Kumara Swamy*
School of Chemistry, University of Hyderabad, Hyderabad - 500046, AP, India
Fax: +91(40)23012460; e-Mail: kckssc@uohyd.ernet.in.;

Abstract

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Abstract

Synthesis of several α-methoxy phosphonates with the phosphorus as a part of 1,3,2-dioxaphosphorinane ring by the simple reaction of (OCH₂CMe₂CH₂O)PCl with acetals is described. Analogous methoxy phosphonates using (±) (C₂₀H₁₂O₂)PCl were also synthesized using the same route. Utility of these phosphonates in the synthesis of vinyl ethers via the Horner-Wadsworth-Emmons [HWE] reaction is demonstrated.

Key words

acetals - vinyl ethers - phosphorus - phosphonates - Horner-Wadsworth-Emmons reaction

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