Spontaneous Regression of an Inflammatory Pseudotumor of the Liver

E. Biecker; A. Zimmermann; J.-F. Dufour

doi:10.1055/s-2003-42928

Zeitschrift für Gastroenterologie, Table of Contents

Z Gastroenterol 2003; 41(10): 991-994
DOI: 10.1055/s-2003-42928

Kasuistik

Spontaneous Regression of an Inflammatory Pseudotumor of the Liver

Spontane Regression eines inflammatorischen Pseudotumors der LeberE. Biecker¹ , A. Zimmermann² , J.-F Dufour¹

¹Institut für klinische Pharmakologie, Universität Bern, Schweiz
²Pathologisches Institut, Universität Bern, Schweiz

Abstract

Zusammenfassung

Inflammatorische Pseudotumoren (IPT) wurden für fast alle Organe und Gewebe beschrieben, finden sich aber nur selten in der Leber. Klinisch präsentieren sich die Patienten in der Regel mit Fieber, Abgeschlagenheit, Gewichtsverlust und oft mit einer Raumforderung im Oberbauch. Die bildgebenden Verfahren allein erlauben in der Regel keine sichere Diagnose, insbesondere die Abgrenzung zu Neoplasien ist schwierig. Prinzipiell ist eine Biopsie zur Diagnosesicherung unumgänglich. Der klinische Verlauf ist meist benigne, allerdings sind aggressive Verlaufsformen bekannt. Bei einem Großteil der beschriebenen Patienten wurde eine Resektion vorgenommen oder die Patienten wurden medikamentös behandelt. Wir schildern eine Patientin mit histologisch gesichertem IPT der Leber, bei der der IPT sich über einige Monate spontan und ohne spezifische Therapie zurückentwickelte.

Abstract

Inflammatory pseudotumors (IPT) have been described for virtually every site in the body but is rare in the liver. The clinical presentation of hepatic IPT is unspecific, patients complain of fever, malaise, weight loss and often of symptoms related to a mass effect. Routine imaging procedures are not sufficient to make the diagnosis and a biopsy is necessary to differentiate IPT from neoplasms. The course of the disease is unpredictable and in most of the reported cases the patients underwent resection or were medically treated. We report a patient with a histologically proven IPT of the liver that regressed spontaneously over several months without any specific treatment.

Schlüsselwörter

Inflammatorischer Pseudotumor - Lebertumor

Key words

Inflammatory pseudotumor - liver tumor

Full Text

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Dr. med. Dr. phil. Erwin Biecker

Medizinische Klinik I, Universitätsklinikum Bonn

Sigmund-Freud-Straße 25

53105 Bonn

Email: Erwin.Biecker1@epost.de