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DOI: 10.1055/s-2003-43219
© Georg Thieme Verlag Stuttgart · New York
Constituents from the Stems of Goniothalamus griffithii
This work was supported by the National Science Foundation of China (Grant No. 39 770 089) and the Applied and Basic Research Foundation of Yunnan province (Grant No. 97B038q)Publication History
Received: January 8, 2003
Accepted: April 18, 2003
Publication Date:
04 November 2003 (online)
![](https://www.thieme-connect.de/media/plantamedica/200309/lookinside/thumbnails/10.1055-s-2003-43219-1.jpg)
Abstract
A new cyclopeptide, grifficyclocin A (1), and a new aporphine alkaloid, griffinin (2) were isolated together with two known styryllactones from the stems of Goniothalamus griffithii. Their structures were identified spectroscopically and chemically. Among them, the griffinin (2) was isolated as the enol form in two tautomers, and the two known styryllactones, goniothalamin (3) and 8-O-acetylgoniotriol (4), showed selective in vitro antitumor activities.
Key words
Goniothalamus griffithii - Annonaceae - cyclopeptide - grifficyclocin A - griffinin - styryllactone
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Dr. Qing Mu
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