Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

Jenny T. Bencardino; Alvand Hassankhani

doi:10.1055/s-2003-43228

Seminars in Musculoskeletal Radiology, Table of Contents

Semin Musculoskelet Radiol 2003; 7(3): 175-186
DOI: 10.1055/s-2003-43228

Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

Jenny T. Bencardino^1,2 , Alvand Hassankhani^2,3

¹Medical Arts Radiological Group, P.C., Bayshore, NY
²Department of Radiology, Harvard Medical School, Boston, MA
³Brookhaven Memorial Hospital Medical Center, Patchogue, NY

Abstract

ABSTRACT

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is characterized by the accumulation of pyrophosphate dihydrate crystals in articular and periarticular tissues. Various terms have been utilized to describe this arthropathy, which has led to some confusion. CPPD crystal deposition disease is among many conditions that may result in crystal deposition within cartilage. Chondrocalcinosis is a pathologic and radiographic term denoting calcification of cartilage within joints including both hyaline articular cartilage and fibrocartilage. Pseudogout is a clinical term applied to an acute inflammatory process in a joint(s) mimicking a gout attack. Pseudogout is just one of the multiple clinical presentations for CPPD crystal deposition disease. Pyrophosphate arthropathy is a term that has been used to describe the peculiar pattern of joint destruction associated with CPPD crystal deposition disease. This article reviews the protean manifestations of CPPD crystal deposition disease with emphasis on diagnostic imaging.

KEYWORDS

Calcium pyrophosphate dihydrate - imaging - pseudogout

Full Text

References

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