Abstract
Two new diastereomeric ferrocenyl triphosphine ligands P3Chir 1 and 2 have been conveniently synthesized through a multi-step reaction sequence starting from (R )-(S )-diphenylphosphinoferrocenylamine [(R )-(S )-PPFA]. Chromatographic resolution of the diborane protected-phosphine oxide derivatives, followed by a stereoconservative reduction/deboronation step, gave the pure triphosphines P3Chir in which the planar chirality of the ferrocenyl unit is combined with phosphorus and carbon stereocenters in an unprecedented molecular assembly.
Key words
chiral - ferrocenes - phosphines - tridentate ligands - chromatographic resolution
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