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Synthesis 2004(2): 237-240
DOI: 10.1055/s-2003-44386
DOI: 10.1055/s-2003-44386
PAPER
© Georg Thieme Verlag Stuttgart · New York
The Formation of β-Lactam Derivatives through the Reaction of Dibenzoylacetylene and Aryl Isocyanates in the Presence of Trivalent Phosphorus Nucleophiles
Further Information
Received
27 August 2003
Publication Date:
18 December 2003 (online)
Publication History
Publication Date:
18 December 2003 (online)
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Abstract
An effective route to novel β-lactams is described. This involves reaction of dibenzoylacetylene and phenyl isocyanate or phenylsulfonyl isocyanate in the presence of trivalent phosphorus nucleophiles.
Key words
triphenylphosphine - trialkyl phosphates - dibenzoylacetylene - aryl isocyanate - β-lactams
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