Abstract
Five new withasteroids, physachenolides A - E were isolated from the acetone and methanol extracts of leaves, flowers and stems of Physalis chenopodifolia Lam. The structural assignments of these compounds were based on spectral evidence. The absolute configuration of physachenolide A was established by X-ray analysis.
Key words
Physalis chenopodifolia
- Solanaceae - Withasteroids - Withanolides - physachenolides A - E
References
-
1 Ray A B, Gupta M. Withasteroids, a growing group of naturally occurring steroidal lactones. In: Herz W, Kirby GW, Moore RE, Steglich W, Tamm Ch, editors Progress Chem. Org. Nat. Prod Vol. 63 Wien; Springer-Verlag 1994: p. 1-106
-
2
Khan P M, Ahmad S, Rubnawaz H, Malik A.
The first report of a withanolide from the family Labiatae.
Phytochemistry.
1999;
51
669-71
-
3
Martínez M.
Revision of Physalis section Epeteiorhiza (Solanaceae). Anales del Instituto de Biología, Universidad Nacional Autónoma de México.
Serie Botánica.
1998;
69
71-117
-
4 Nee M. The systematics of the lesser known edible Solanaceae of the New World. In: Hawkes JG, Lester, RN, Nee M, Estrada, editors Solanaceae III: Taxonomy, Chemistry, Evolution. The Royal Botanical Gardens Kew and the Linnean Society of London Surrey 1991: p. 365-8
-
5 Montes S H. Tomate de cáscara (Physalis philadelphica Lam.) In: Ortega PR, Palomino HG, Castillo GF, González HVA, Levira MM, editores Avances en el estudio de los recursos fitogenéticos de México. Chapingo; SOMEFI 1991: p. 251-9
-
6 Instituto Nacional Indigenista. Atlas de las plantas de la medicina tradicional mexicana. Vilamar AA, coordinador. Vol. III México; 1994: p. 1350-1
-
7
Altomare A, Cascarano G, Giacovazzo C, Guagliardi A, Burla M C, Polidori G, Camalli M.
SIR-92. A program for automatic solution of crystal structures by direct methods.
J Appl Crystallogr.
1994;
27
435
-
8 Sheldrick G M. SHELXL-97, Program of refining of crystal structures. Germany; University of Göttingen 1999
-
9
Khan P M, Malik A, Ahmad S, Nawaz H R.
Withanolides from Ajuga parviflora
.
J Nat Prod.
1999;
62
1290-2
-
10
Dinan L N, Sarker S D, Sik V.
28-Hydroxywithanolide E from Physalis peruviana
.
Phytochemistry.
1997;
44
509-12
-
11
Ksebati M B, Schmitz F J.
Mineabolides: A group of withanolides from a soft coral, Minabea sp.
J Org Chem.
1988;
53
3926-9
-
12
Shingu K, Miyagawa M, Yahara S, Nohara T.
Physapruins A and B, two new withanolides from Physalis pruinosa
.
Chem Pharm Bull.
1993;
41
1873-5
-
13
Gottlieb H E, Kirson I.
13C NMR spectroscopy of withanolides and other highly oxygenated C28 steroids.
Org Magn Reson.
1981;
16
20-5
1 Contribution No. 2459 of the Instituto de Química, UNAM.
Emma Maldonado Jiménez, M.Sc.
Instituto de Química
Universidad Nacional Autónoma de México
Circuito Exterior
Ciudad Universitaria
Coyoacán 04510 D.F.
México
Fax: +5255-5616-2217
eMail: emmaldonado@correo.unam.mx
