Some new ethynyl ketones containing ferrocenyl moieties were prepared conveniently by coupling ferrocenylethyne with acyl chlorides in the presence of a catalytic amount of PdCl2(PPh3)2/PdBzCl(PPh3)2-CuI. This coupling reaction proceeded smoothly in a dry argon atmosphere at room temperature and gave coupling products in satisfactory yields.
ferrocene - ferrocenylethynyl ketones - Sonogashira coupling - acyl chlorides - Pd-catalysis