Synthesis of Ferrocenylethynyl Ketones by Coupling of Ferrocenylethyne with Acyl Chlorides

Juxing Yin; Xiaojun Wang; Yongmin Liang; Xiaoli Wu; Baohua Chen; Yongxiang Ma

doi:10.1055/s-2004-815934

SHORTPAPER

Synthesis of Ferrocenylethynyl Ketones by Coupling of Ferrocenylethyne with Acyl Chlorides

Juxing Yin, Xiaojun Wang, Yongmin Liang, Xiaoli Wu, Baohua Chen*, Yongxiang Ma
National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
Fax: +86(931)8912582 ; e-Mail: chbh@lzu.edu.cn ;

Abstract

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Abstract

Some new ethynyl ketones containing ferrocenyl moieties were prepared conveniently by coupling ferrocenylethyne with acyl chlorides in the presence of a catalytic amount of PdCl₂(PPh₃)₂/PdBzCl(PPh₃)₂-CuI. This coupling reaction proceeded smoothly in a dry argon atmosphere at room temperature and gave coupling products in satisfactory yields.

Key words

ferrocene - ferrocenylethynyl ketones - Sonogashira coupling - acyl chlorides - Pd-catalysis

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