Synthesis, Table of Contents PAPER © Georg Thieme Verlag Stuttgart · New York Substituted Selenolo[2,3-b]thiophenes and Selenophenes Starting from Ketene Dithioacetals Geoffroy Sommen, Alain Comel, Gilbert Kirsch*Laboratoire d’Ingénierie Moléculaire et Biochimie Pharmacologique, 1 Boulevard Arago, Metz Technopôle, CP 87811, 57078 METZ Cedex 3, Francee-Mail: kirsch@sciences.univ-metz.fr; Recommend Article Abstract Buy Article All articles of this category Abstract Substituted selenolo[2,3-b]thiophenes 4 and selenophenes 5 can be easily synthesized in two steps from ketene dithioacetals 1. Key words bicyclic compounds - nucleophilic aromatic substitution - cyclization - selenium - thiols Full Text References References 1 Li Y. Cao Z. Neurosci. Lett. 2002, 330: 69 2 Porciúncula LO. Schmidt AP. Coitinho AS. Vinadé L. Izquierdo I. Rocha JBT. Souza DO. Eur. J. Pharmacol. 2002, 451: 165 3 Christiaens L. In Comprehensive Heterocyclic Chemistry Vol. 2: Katritzky AR. Rees CW. Scriven EFV. Elsevier Science Ltd.; Amsterdam: 1996. p.746-747 4 Boles JO. Henderson J. Hatch D. Silks LA. Biochem. Biophys. Res. Commun. 2002, 298: 257 5 Bae JH. Alefelder S. Kaiser JT. Friedrich R. Moroder L. Huber R. Budisa N. J. Mol. Biol. 2001, 309: 925 6 Sommen G. Comel A. Kirsch G. Synthesis 2003, 735 7 Litvinov VP. Gol’dfarb YL. In Advanced Heterocyclic Chemistry Vol. 19: Katritzky AR. Boulton AJ. Academic Press; New York: 1976. p.123 8 Comel A. Kirsch G. J. Heterocycl. Chem. 2001, 38: 1167 ; and references cited therein 9a Junjappa H. Ila H. Asokan CV. Tetrahedron 1990, 46: 5423 9b Yokoyama M. Togo H. Kondo S. Sulfur Reports 1990, 10: 23 9c Tominaga Y. J. Heterocycl. Chem. 1989, 26: 1167 9d Sharma S. Sulfur Reports 1989, 8: 327 9e Brandsma L. Nedolya NA. Tarasova OA. Trofimov BA. Chem. Hetercycl. Compd. 2000, 36: 1241 10 Sommen G. Comel A. Kirsch G. Synlett 2003, 855 11 Sommen G. Comel A. Kirsch G. Tetrahedron 2003, 59: 1557
