Synthesis of Nitrated Thienylphosphonates via Michaelis-Arbuzov-Type Rearrangement

Abstract

A facile, catalyst-free synthesis of diethyl thienylphosphonates under mild conditions without solvent is described. The desired products were obtained, via a Michaelis-Arbuzov-type rearrangement, from various activated thienyl halides by reacting with triethyl phosphite.

Michaelis-Arbuzov rearrangement - phosphorus - heterocycles - thienylphosphonates - halides

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