Minim Invasive Neurosurg 2004; 47(3): 131-135
DOI: 10.1055/s-2004-818492
Original Article
© Georg Thieme Verlag Stuttgart · New York

Prediction of Impending Rupture in Aneurysms Using 4D-CTA: Histopathological Verification of a Real-Time Minimally Invasive Tool in Unruptured Aneurysms

Y.  Kato1 , M.  Hayakawa1 , H.  Sano1 , M.  V.  Sunil1 , S.  Imizu1 , M.  Yoneda1 , S.  Watanabe1 , M.  Abe2 , T.  Kanno1
  • 1Department of Neurosurgery, Fujita Health University, Toyoake, Japan
  • 2Department of Neuropathology, Fujita Health University, Toyoake, Japan
Further Information

Publication History

Publication Date:
02 September 2004 (online)

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Abstract

The authors describe the use of a 4D-CT angiogram to predict impending rupture in intact aneurysms, as a real-time, less invasive imaging technique. Histopathological verification and immunostaining of the bleb site performed on the study population reveals the significant predictive value of this tool. The point of maximum amplitude of pulsation of the aneurysm wall in unison with the RR interval of the electrocardiogram determines the potential rupture point. This helps in prioritizing the intervention for unruptured aneurysm cases, provides an effective screening of the high-risk population, and aids preoperative planning of clip application.

References

Prof. Yoko Kato,  M. D.

Department of Neurosurgery · Fujita Health University

Toyoake

Aichi 4701192

Japan

Phone: +81-562-93-9253

Fax: +81-562-93-3118

Email: kyoko@fuita-hu.ac.jp