Planta Med 2004; 70(3): 276-278
DOI: 10.1055/s-2004-818924
Letter
© Georg Thieme Verlag Stuttgart · New York

Antitubercular and Antiplasmodial Constituents of Abrus precatorius

Chutima Limmatvapirat1 , Sinenart Sirisopanaporn2 , Prasat Kittakoop3
  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Silpakorn University, Nakorn-Pathom, Thailand
  • 2Junior Science Talent Project, Thailand
  • 3National Center for Genetic Engineering and Biotechnology (BIOTEC), NSTDA, Klong Luang, Pathumthani, Thailand
We thank the Biodiversity Research and Training Program (BRT) and Faculty of Pharmacy (Silpakorn University) for financial support
Further Information

Publication History

Received: September 18, 2003

Accepted: December 12, 2003

Publication Date:
23 March 2004 (online)

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Abstract

A known isoflavanquinone, abruquinone B (1), and a new derivative, abruquinone G (2), were isolated from the aerial parts of Abrus precatorius. Chemical structures of these compounds were elucidated by spectral analyses. While 1 exhibited antitubercular, antiplasmodial and cytotoxic activities, compound 2 showed mild antiviral and cytotoxic activities.

References

Dr. Chutima Limmatvapirat

Department of Pharmaceutical Chemistry

Faculty of Pharmacy

Silpakorn University

Nakorn-Pathom 73000

Thailand

Phone: +66-34-255800 ext. 2125 or 2552

Fax: +66-34-255801

Email: chutima@email.pharm.su.ac.th