Three diabetic patients with leg or foot ulcers unresponsive to conventional therapies
were treated with topical application of Nerve Growth Factor (NGF). The results showed
that NGF promotes healing after 5 - 14 weeks of treatment. This study suggests that
the use of topical application of NGF may represent a new useful tool for the management
of difficult diabetic ulcers.
Nerve growth factor - diabetes - cutaneous ulcer - neuropathy