Abstract
The asymmetric dihydroxylation reaction of early stage and advanced Bryostatin C-ring precursors was evaluated. For homoallylic ethers and alcohols, several AD ligands were investigated including a novel class of quinidine-alkynes.
Key words
asymmetric dihydroxylation - Bryostatin - quinidine-based ligands - double stereoinduction -
Cinchona alkynes
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[3
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