Zusammenfassung
Im Rahmen des allgemeinen Trends zur Einnahme von Nahrungsergänzungsmitteln werden derzeit auch sehr erfolgreich Basenprodukte beworben und vertrieben. Dabei wird die chronische Übersäuerung des Menschen durch Nahrung und Umwelt als Argumentationsgrundlage verwendet. In wieweit eine Übersäuerung des Gesamtorganismus für gesunde Menschen wirklich relevant ist, wird jedoch kaum durch wissenschaftliche Untersuchungen belegt. In dieser Übersichtsarbeit wird insbesondere diese Problematik analysiert. Des weiteren werden neben einem kurzen Exkurs in die Grundlagen des Säure-Basen-Haushalts positive bzw. potenziell negative Auswirkungen von Basen auf den Menschen besprochen.
Summary
Owing to a general trend for dietary supplementation, the consumption of base products is gaining more and more popularity. The principal reason for this is the theory about the chronic acidification of the body through diet and environment. However, the relevance of this argumentation for a healthy person is rarely proven by scientific investigations. This article concentrates on this topic. Additionally, the basics of acid-base physiology are reviewed and potential positive or harmful effects of base products on the body are discussed.
Schlüsselwörter
Säure-Basen-Haushalt - Übersäuerung - Basenpulver
Key words
Acid-base physiology - diet-induced metabolic acidosis - alkaline products
Literatur
-
1
Adler S.
The simultaneous determination of muscle cell pH using a weak acid and weak base.
J Clin Invest.
1972;
51
256-265
-
2
Barzel US, Massey LK.
Excess dietary protein can adversely affect bone.
J Nutr.
1998;
128
1051-1053
-
3
Buclin T, Cosma M, Appenzeller M. et al. .
Diet acids and alkalis influence calcium retention in bone.
Osteoporos Int.
2001;
12
493-499
-
4
Bushinsky DA.
Acid-base imbalance and the skeleton.
Eur J Nutr.
2001;
40
238-244
-
5
Ganapathy V, Leibach FH.
Protons and regulation of biological functions.
Kidney Int Suppl.
1991;
33
4-10
-
6
Kurtz I, Maher T, Hulter HN. et al. .
Effect of diet on plasma acid-base composition in normal humans.
Kidney Int.
1983;
24
670-680
-
7
Lemann Jr J, Gray RW, Pleuss JA.
Potassium bicarbonate, but not sodium bicarbonate, reduces urinary calcium excretion and improves calcium balance in healthy men.
Kidney Int.
1989;
35
688-695
-
8
Lindinger MI, Franklin TW, Lands LC. et al. .
NaHCO(3) and KHCO(3) ingestion rapidly increases renal electrolyte excretion in humans.
J Appl Physiol.
2000;
88
540-550
-
9
Lutz J.
Calcium balance and acid-base status of women as affected by increased protein intake and by sodium bicarbonate ingestion.
Am J Clin Nutr.
1984;
39
281-288
-
10
Maurer M, Riesen W, Muser J. et al. .
Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans.
Am J Physiol Renal Physiol.
2003;
284
32-40
-
11
McCarron DA, Rankin LI, Bennett WM. et al. .
Urinary calcium excretion at extremes of sodium intake in normal man.
Am J Nephrol.
1981;
1
84-90
-
12
Murayama T, Sakai N, Yamada T, Takano T.
Role of the diurnal variation of urinary pH and urinary calcium in urolithiasis: a study in outpatients.
Int J Urol.
2001;
8
525-531
-
13
Remer T, Manz F.
Potential renal acid load of foods and its influence on urine pH.
J Am Diet Assoc.
1995;
95
791-797
-
14
Sakhaee K, Nicar M, Hill K, Pak CY.
Contrasting effects of potassium citrate and sodium citrate therapies on urinary chemistries and crystallization of stone-forming salts.
Kidney Int.
1983;
24
348-352
-
15
Sebastian A, Harris ST, Ottaway JH. et al. .
Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate.
N Engl J Med.
1994;
330
1776-1781
-
16
Sebastian A, Sellmeyer DE, Stone KL, Cummings SR.
Dietary ratio of animal to vegetable protein and rate of bone loss and risk of fracture in postmenopausal women.
Am J Clin Nutr.
2001;
74
411-412
-
17
Tucker KL, Hannan MT, Chen H. et al. .
Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women.
Am J Clin Nutr.
1999;
69
727-736
Ao.Univ.-Prof. Dr. Cem Ekmekcioglu
Institut für Physiologie, Medizinische Universität Wien
Schwarzspanierstraße 17
A-1090 Wien
Email: cem.ekmekcioglu@meduniwien.ac.at
