Endoscopy 2004; 36(8): 738-742
DOI: 10.1055/s-2004-825672
Case Report
© Georg Thieme Verlag KG Stuttgart · New York

External Pancreatic Fistulas Resistant to Conventional Endoscopic Therapy: Endoscopic Closure With N-Butyl-2-Cyanoacrylate (Glubran 2)

M.  Mutignani1 , A.  Tringali1 , E.  Khodadadian1 , L.  Petruzziello1 , C.  Spada1 , G.  Spera1 , P.  Familiari1 , G.  Costamagna1
  • 1Digestive Endoscopy Unit, Catholic University, Rome, Italy
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Publikationsverlauf

Submitted 13 January 2004

Accepted after Revision 7 April 2004

Publikationsdatum:
28. Juli 2004 (online)

Preview

External pancreatic fistulas may follow abdominal surgery or injury. While most respond to conservative management or endoscopic intervention, others might require surgery for complete healing. We report four cases of patients with external pancreatic fistulas that failed to respond to conservative management and drainage. N-butyl-2-cyanoacrylate surgical glue (Glubran 2) was directly injected into the fistulous tract. The fistulas closed within 24 hours of the Glubran 2 injection in three cases (75 %). In patients with external pancreatic fistulas that fail to respond to conservative and endoscopic drainage, injection of Glubran 2 directly into the fistulous tract may lead to closure, thus avoiding the need for surgical intervention.

References

G. Costamagna, M. D.

Digestive Endoscopy Unit · Università Cattolica del Sacro Cuore · A. Gemelli University Hospital

Largo A. Gemelli 8 · 00168 Rome · Italy

Fax: +39-06-30156581

eMail: gcostamagna@rm.unicatt.it