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DOI: 10.1055/s-2004-825672
External Pancreatic Fistulas Resistant to Conventional Endoscopic Therapy: Endoscopic Closure With N-Butyl-2-Cyanoacrylate (Glubran 2)
Publikationsverlauf
Submitted 13 January 2004
Accepted after Revision 7 April 2004
Publikationsdatum:
28. Juli 2004 (online)
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External pancreatic fistulas may follow abdominal surgery or injury. While most respond to conservative management or endoscopic intervention, others might require surgery for complete healing. We report four cases of patients with external pancreatic fistulas that failed to respond to conservative management and drainage. N-butyl-2-cyanoacrylate surgical glue (Glubran 2) was directly injected into the fistulous tract. The fistulas closed within 24 hours of the Glubran 2 injection in three cases (75 %). In patients with external pancreatic fistulas that fail to respond to conservative and endoscopic drainage, injection of Glubran 2 directly into the fistulous tract may lead to closure, thus avoiding the need for surgical intervention.
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G. Costamagna, M. D.
Digestive Endoscopy Unit · Università Cattolica del Sacro Cuore · A. Gemelli University Hospital
Largo A. Gemelli 8 · 00168 Rome · Italy
Fax: +39-06-30156581
eMail: gcostamagna@rm.unicatt.it