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DOI: 10.1055/s-2004-827163
Hepatoprotective Flavonol Glycosides from the Aerial Parts of Rodgersia podophylla
This work was supported by a grant of the Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea. (00-PJ1-PG1-CH14-0006)Publication History
Received: October 30, 2003
Accepted: March 7, 2004
Publication Date:
01 July 2004 (online)

Abstract
A new acylated flavonoid, quercetin 3-O-α-L-(5″-O-acetyl)-arabinofuranoside (1), along with six known flavonoids (2 - 7) were isolated from the aerial parts of Rodgersia podophylla. The new flavonoid 1 exhibited 50.1 % hepatoprotective activity at a concentration of 100 μM, and the three known compounds 3, 5 and 6 showed hepatoprotective activities at a concentration of 50 μM (45.7, 50.8 and 57.3 %, respectively) by using the primary cultures of rat hepatocytes injured by H2O2.
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Prof. Jinwoong Kim
College of Pharmacy
Seoul National University
San 56-1
Shinlim-dong
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Seoul 151-742
Korea
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Email: jwkim@snu.ac.kr