Hepatoprotective Flavonol Glycosides from the Aerial Parts of Rodgersia podophylla

Abstract

A new acylated flavonoid, quercetin 3-O-α-L-(5″-O-acetyl)-arabinofuranoside (1), along with six known flavonoids (2 - 7) were isolated from the aerial parts of Rodgersia podophylla. The new flavonoid 1 exhibited 50.1 % hepatoprotective activity at a concentration of 100 μM, and the three known compounds 3, 5 and 6 showed hepatoprotective activities at a concentration of 50 μM (45.7, 50.8 and 57.3 %, respectively) by using the primary cultures of rat hepatocytes injured by H₂O₂.

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