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Semin intervent Radiol 2003; 20(4): 341-345
DOI: 10.1055/s-2004-828945
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Radiofrequency Ablation and Radiotherapy: Complementing Treatments for Solid Tumors

Thomas A. DiPetrillo1 , Damian E. Dupuy2
  • 1Department of Radiation Oncology, Brown University School of Medicine, Providence, Rhode Island
  • 2Department of Radiology, Brown University School of Medicine, Providence, Rhode Island
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Publication History

Publication Date:
20 July 2004 (online)

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ABSTRACT

This article outlines the complimentary role of radiofrequency ablation used in conjunction with radiotherapy. It defines the theory behind the treatment as well as specific clinical applications for the combination of this technique. It outlines the practical aspects of the combination therapy including the timing of the radiofrequency ablation versus radiotherapy, the fractionation of the doses, and the radiation doses.

KEYWORDS

Radiotherapy - radiofrequency ablation - tumors

REFERENCES

  • 1 Goldberg S N, Dupuy D E. Image-guided radiofrequency tumor ablation: challenges and opportunities, part I.  J Vasc Interv Radiol . 2001;  12 1021-1032
    PubMedSearch in Google Scholar
  • 2 Dupuy D E, Goldberg S N. Image-guided radiofrequency tumor ablation: challenges and opportunities, part II.  J Vasc Interv Radiol . 2001;  12 1135-1148
    CrossrefPubMedSearch in Google Scholar
  • 3 Dupuy D E, Zagoria R J, Akerley W, Mayo-Smith W W, Kavanaugh P V, Safran H. Percutaneous radiofrequency ablation of malignancies in the lung.  AJR Am J Roentgenol . 2000;  174 57-59
    PubMedSearch in Google Scholar
  • 4 Dupuy D E, Monchik J M, Decrea C, Pisharodi L. Radiofrequency ablation of regional recurrence from well-differentiated thyroid malignancy.  Surgery . 2001;  130 971-977
    CrossrefPubMedSearch in Google Scholar
  • 5 Dupuy D E, Mayo-Smith W W, Abbott G, DiPetrillo T. Clinical applications of radiofrequency tumor ablation in the thorax.  Radiographics . 2002;  Spec No S259-269
    PubMedSearch in Google Scholar
  • 6 Gervais D A, McGovern F J, Wood B J, Goldberg S N, McDougal W S, Mueller P R. Radiofrequency ablation of renal cell carcinoma: early clinical experience.  Radiology . 2000;  217 665-672
    CrossrefPubMedSearch in Google Scholar
  • 7 Nishida T, Inoue K, Kawata Y. et al . Percutaneous radiofrequency ablation of lung neoplasms: a minimally invasive strategy for inoperable patients.  J Am Coll Surg . 2002;  196 426-430
    PubMedSearch in Google Scholar
  • 8 Schaefer O, Lohrmann C, Langer M. CT-guided radiofrequency ablation of a bronchogenic carcinoma.  Br J Radiol . 2003;  76(904) 268-270
    PubMedSearch in Google Scholar
  • 9 Rohde D, Albers C, Mahnken A, Tacke J. Regional thermoablation of local or metastatic renal cell carcinoma.  Oncol Rep . 2003;  10(3) 753-757
    PubMedSearch in Google Scholar
  • 10 Wood B J, Ramkaransingh J R, Fojo T, Walther M M, Libutti S K. Percutaneous tumor ablation with radiofrequency.  Cancer . 2002;  15(94) 443-451
    PubMedSearch in Google Scholar
  • 11 Mirza A N, Fornage B D, Sneige N. et al . Radiofrequency ablation of solid tumors.  Cancer J . 2001;  7(2) 95-102
    PubMedSearch in Google Scholar
  • 12 Bui Q T, Dupuy D E. Percutaneous CT-guided radiofrequency ablation of an adenoid cystic carcinoma of the head and neck.  AJR Am J Roentgenol . 2002;  179(5) 1333-1335
    PubMedSearch in Google Scholar
  • 13 Friedman M A, Altemus R, Wood B. Radiofrequency ablation in a previously irradiated liver.  J Vasc Interv Radiol . 2003;  14 1345-1348
    PubMedSearch in Google Scholar
  • 14 Rubin P, Johnston C J, Williams J P, Finkelstein J N. A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis.  Int J Radiat Oncol Biol Physiol . 1995;  33(1) 99-109
    CrossrefPubMedSearch in Google Scholar
  • 15 Hall E J. Radiobiology for the Radiologist, 5th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2000 . 
  • 16 Schmidt-Ullrich R K. Molecular targets in radiation oncology.  Oncogene . 2003;  22(37) 5730-5733
    CrossrefPubMedSearch in Google Scholar
  • 17 Dupuy D E, Chauhan B, Ready N, DiPetrillo T, Gaissert H, Fenton M A. Radiofrequency ablation followed by conventional radiotherapy for inoperable stage I non-small cell lung cancer.  American Society of Clinical Oncology Proceedings . 2003;  22 2632
    PubMedSearch in Google Scholar
  • 18 Jain S K, Dupuy D E, Cardarelli G A, Zheng Z, DiPetrillo T A. Percutaneous radiofrequency ablation of lung malignancies: combined treatment with brachytherapy.  AJR Am J Roentgenol . 2003;  181 711-715
    CrossrefPubMedSearch in Google Scholar