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Synthesis 2004(15): 2471-2478
DOI: 10.1055/s-2004-831204
DOI: 10.1055/s-2004-831204
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Ferrocenyl-1-(4-pyridylmethyl)- and Ferrocenyl-1-[2-hydroxy-1,2-bis(4-pyridyl)ethyl]pyrazoles
Further Information
Received
9 April 2004
Publication Date:
02 September 2004 (online)
Publication History
Publication Date:
02 September 2004 (online)
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Abstract
Pyridine-4-carbaldehyde reacts with ferrocenyl-4,5-dihydropyrazoles to yield ferrocenyl-1-(4-pyridylmethyl)pyrazoles and ferrocenyl-1-[2-hydroxy-1,2-bis(4-pyridyl)ethyl]pyrazoles. The structures of the compounds obtained were established based on spectroscopic (IR, mass, 1H and 13C NMR) data. X-ray diffraction data for 4-[3-(p-bromophenyl)-5-ferrocenyl-1-(4-pyridyl)-methylpyrazole corroborate its structure.
Key words
α,β-unsaturated ketones - ferrocenylpyrazolines - ferrocenyl-1-(4-pyridylmethyl)pyrazoles - ferrocenyl-1-[2-hydroxy-1,2-bis(4-pyridyl)ethyl]pyrazoles
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