Aqueous Medium Radical Addition to Ketimines with a Phenolic Hydroxyl Group

Hideto Miyabe; Yousuke Yamaoka; Yoshiji Takemoto

doi:10.1055/s-2004-834803

LETTER

Aqueous Medium Radical Addition to Ketimines with a Phenolic Hydroxyl Group

Hideto Miyabe, Yousuke Yamaoka, Yoshiji Takemoto*
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan
Fax: +81(75)7534569; e-Mail: takemoto@pharm.kyoto-u.ac.jp;

Abstract

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Abstract

Intermolecular alkyl radical addition to ketimines having 2-phenolic hydroxyl group proceeded effectively in aqueous media, providing the novel method for construction of all-substituted sp³-hybridized carbon center.

Key words

radical - imine - ketimine - water - aqueous media

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Referenzen

References

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