Am J Perinatol 2004; 21(7): 421-424
DOI: 10.1055/s-2004-835313
Copyright © 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Sudden and Unexpected Fetal Death Associated with Agenesis of the Arcuate Nucleus in the Medulla Oblongata

Ralph A. Franciosi1 , Annette D. Segura1
  • 1Department of Pathology, Children's Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee, Wisconsin
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Publikationsverlauf

Publikationsdatum:
08. Oktober 2004 (online)

Abnormalities have been reported in the medullary arcuate nucleus (ARCN) in unexpected late fetal death. They speculated that this developmental anomaly may underlie cardioventilatory abnormalities intrapartum and postpartum. This article describes a case of an unexpected late fetal death associated with absence of the ARCN.

REFERENCES

  • 1 Altshuler G. Chorangiosis: an important placental sign of neonatal morbidity and mortality.  Arch Pathol Lab Med. 1984;  108 71-74
  • 2 Benirschke K, Kaufmann P. Pathology of the Human Placenta. 4th ed. New York; Springer-Verlag 1999: 786-787
  • 3 Fanaroff A A, Martin R J. Neonatal-Perinatal Medicine. 5th ed. St. Louis, MO; Mosby-Yearbook Inc. 1992: 277-278
  • 4 Matturri L, Minoli I, Lavezzi A M, Cappellini A, Ramos S, Rossi L. Hypoplasia of medullary arcuate nucleus in unexpected late fetal death (stillborn infants): a pathologic study.  Pediatrics. 2002;  109 1-5
  • 5 Kinney H C, Filiano J J, White W F. The medullary serotonergic network deficiency hypothesis in the sudden infant death syndrome. A review of a 15-year study of a single database.  J Neuropathol Exp Neurol. 2001;  60 228-247
  • 6 Fifer W P, Myers M M. Sudden fetal and infant death: shared characteristics and distinctive features.  Semin Perinatol. 2002;  26 89-96

Ralph A FranciosiM.D. 

Department of Pathology Children's Hospital of Wisconsin

9000 West Wisconsin Avenue, Milwaukee, WI 53226

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