A Facile Synthesis of Chroman-4-ones and 2,3-Dihydroquinolin-4-ones with Quaternary Carbon Using Intramolecular Stetter Reaction Catalyzed by Thiazolium Salt

Taiju Nakamura; Osamu Hara; Tsutomu Tamura; Kazuishi Makino; Yasumasa Hamada

doi:10.1055/s-2004-835666

LETTER

A Facile Synthesis of Chroman-4-ones and 2,3-Dihydroquinolin-4-ones with Quaternary Carbon Using Intramolecular Stetter Reaction Catalyzed by Thiazolium Salt

Taiju Nakamura^a, Osamu Hara^b, Tsutomu Tamura^a, Kazuishi Makino^a, Yasumasa Hamada*^a
^a Graduate School of Pharmaceutical Sciences, Chiba University, Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan
^b Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya 460-8503, Japan
Fax: +81(43)2902987; e-Mail: hamada@athenaeum.p.chiba-u.ac.jp;

Abstract

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Abstract

Chroman-4-ones and 2,3-dihydroquinolin-4-ones with quaternary carbon were efficiently synthesized by intramolecular Stetter reaction catalyzed by thiazolium salts.

Key words

Stetter reaction - chroman-4-one - 2,3-dihydroquinolin-4-one - quaternary carbon - thiazolium salt

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References

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