Wertigkeit der Positronenemissionstomographie für das Staging beim Ösophaguskarzinom

Zusammenfassung

Der Wert der Positronenemissionstomographie mit ¹⁸F-18-Fluorodesoxyglukose (FDG-PET) für das primäre Staging und das posttherapeutische Restaging beim Ösophaguskarzinom wurde in verschiedenen aktuellen Studien untersucht. Die meisten Studien vergleichen die Ergebnisse der FDG-PET mit denen der Computertomographie und/oder der endoskopischen Ultraschalluntersuchung. Die verschiedenen Autoren stimmen darin überein, dass der klinische Einsatz der FDG-PET sowohl die Identifikation von Lymphknotenmetastasen als auch die von Metastasen in anderen Organen verbessert. Eine zunehmende Zahl von Untersuchern zeigte darüber hinaus die Aussagekraft der FDG-PET für die Analyse des Ansprechens des Ösophaguskarzinoms bei neoadjuvanter Radiochemotherapie sowie für die Vorhersage des Langzeitüberlebens.

Abstract

Positron emission tomography with ¹⁸F-Florodesoxyglucose (FDG-PET) was recently evaluated by several studies for staging and posttherapeutical re-staging of esophageal cancer. Most studies compared the FDG-PET results to CT and/or endoscopic ultrasonography. The different authors agreed that the use of FDG-PET improves the identification of lymph node metastases as well as of metastases in other organs. A growing number of investigators also showed the value of FDG-PET for the response analysis after neoadjuvant or concurrent radiochemotherapy resp. the prediction of the long-term survival.

Positronenemissionstomographie - PET - Ösophaguskarzinom - Staging

positron emission tomography - PET - esophageal cancer - staging

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