Am J Perinatol 2005; 22(2): 91-97
DOI: 10.1055/s-2005-837739
Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Left Ventricular Myocardial Performance in the Fetus with Severe Tricuspid Valve Disease and Tricuspid Insufficiency

Noboru Inamura1 , Mio Taketazu2 , Jeffrey F. Smallhorn2 , Lisa K. Hornberger2
  • 1Department of Pediatric Cardiology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan
  • 2Fetal Cardiac Program, Division of Cardiology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada
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Publikationsverlauf

Publikationsdatum:
24. Februar 2005 (online)

ABSTRACT

We sought to determine whether left ventricular (LV) function is abnormal in a fetus with severe tricuspid valve disease (TVD), and whether it may contribute to the outcome. We measured the LV Tei index (including isovolumic relaxation [IRT], contraction, and ejection times) in 31 fetuses with TVD, compared the data with measurements from 32 normal fetuses, and correlated these measurements with pulmonary morphology and outcome. LV Tei index was significantly greater, ejection times shorter, and IRT longer in TVD compared with controls. The Tei index was highest in fetuses with either pulmonary insufficiency or atresia compared with those with forward flow. Finally, LV Tei index was significantly greater in fetuses with fetal (n = 5) or neonatal (n = 9) demise than in neonatal survivors (n = 7). Global LV performance as assessed by the Tei index is abnormal in TVD and likely contribute to the high mortality associated with TVD.

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Noboru InamuraM.D. 

Department of Pediatric Cardiology, Osaka Medical Center and Research Institute for Maternal and Child Health

840 Murodo-cho, Izumi, Osaka 594-1101, Japan