Background and Study Aims: Surgical creation of a small gastric pouch with a restricted outlet is a well-established option for the treatment of morbid obesity. This report describes initial experience with endoscopic transoral stomach partition using a newly designed suturing apparatus.
Materials and Methods: A fresh porcine stomach was placed in the Erlangen model. A prototype suture device, incorporating a curved needle and an intracorporeal tightening mechanism, was used in this procedure. A long fishing line was first introduced into the stomach, with the two ends left outside. The suturing device, premounted outside a standard gastroscope, was inserted into the stomach and delivered several stitches attaching the fishing line to both the anterior and posterior walls along the line for the stomach to be partitioned. Five throws of half-hitches were tied onto the fishing line extracorporeally and separately pushed into place, creating a gastric pouch just below the esophagogastric junction. A flexible sheath of 8 cm long was then put on one side of the fishing line and pushed into the stomach. Additional extracorporeal knots were tied on the fishing line, forming a restrictive ring at the outlet of the pouch. The ring was then anchored to the stomach wall with similar endosutures.
Results: The proximal gastric pouch, with an estimated volume of approximately 100 ml, was successfully created with a restrictive band at its outlet. All of the stitches were securely sutured, with consistent penetration of the muscular layer of the stomach wall.
Conclusions: In a bench model, it is technically possible to accomplish transoral gastroplasty endoscopically with an intraluminal suturing device. Further live animal studies will be needed in order to confirm the efficacy and safety of this procedure before clinical application.
References
1
Flegal K M, Carroll M D, Odgen C L, Johnson C L.
Prevalence and trends in obesity among US adults, 1999 - 2000.
JAMA.
2002;
288
1723-1727
2
Wolf A M, Colditz G A.
Current estimates of the economic cost of obesity in the United States.
Obes Res.
1998;
6
97-106
3
Must A, Spadano J, Coakley E H. et al .
The disease burden associated with overweight and obesity.
JAMA.
1999;
282
1523-1529
4
Brolin R E.
Bariatric Surgery and long-term control of morbid obesity.
JAMA.
2002;
288
2793-2796
5
O’Brien P E, Dixon J B.
Laparoscopic adjustable gastric banding in the treatment of morbid obesity.
Arch Surg.
2003;
138
376-382
6
Cottam D R, Mattar S G, Schauer P R.
Laparoscopic era of operations for morbid obesity.
Arch Surg.
2003;
138
367-375
7
Neumann M, Hochberger J, Felzmann T. et al .
The Erlangen Endo-Trainer.
Endoscopy.
2001;
33
887-890
8
Hu B, Sun L, Lau J YW. et al .
Endoscopic suturing without extracorporeal knots: the Eagle Claw V [abstract].
Gastrointest Endosc.
2004;
59
AB114
9
Mason E E.
Vertical banded gastroplasty for obesity.
Arch Surg.
1982;
117
701-706
10 Kuzmak L I. Gastric banding. In: Dietel M, ed Surgery for the morbidly obese patient. Philadelphia; Lea and Febiger 1989: 225
11
Balsiger B M, Poggio J L, Mai J. et al .
Ten and more years after vertical banded gastroplasty as primary operation for morbid obesity.
J Gastrointest Surg.
2000;
4
598-605
12
Morino M, Toppino M, Bonnet G. et al .
Laparoscopic vertical banded gastroplasty for morbid obesity: assessment of efficacy.
Surg Endosc.
2002;
16
1566-1572
13
Favretti F, Cadiere G M, Segato G. et al .
Laparoscopic banding: selection and technique in 830 patients.
Obes Surg.
2002;
12
385-390
14
O’Brien P E, Dixon J B, Brown W. et al .
The laparoscopic adjustable gastric band (Lap-Band): a prospective study of medium-term effects on weight, health and quality of life.
Obes Surg.
2002;
12
652-660
15
Garren M, Garren L, Giordano F.
The Garren gastric bubble: an Rx for the morbidly obese.
Endosc Rev.
1984;
1
57-60
16
Hogan R B, Johnston J H, Long B W. et al .
A double-blind, randomized, sham-controlled trial of the gastric bubble for obesity.
Gastrointest Endosc.
1989;
35
381-385
17
Kramer F M, Stunkard A J, Spiegel T A. et al .
Limited weight losses with a gastric balloon.
Arch Intern Med.
1989;
149
411-413
18
Wahlen C H, Bastens B, Herve J. et al .
The BioEnterics intragastric balloon (BIB): how to use it.
Obesity Surg.
2001;
11
524-527
19
Galloro G, de Palma G D, Catanzano C.
Preliminary endoscopic technical report of a new silicone intragastric balloon in the treatment of morbid obesity.
Obes Surg.
1999;
9
68-71
20
Totte E, Hendrickx L, Pauwels M, van Hee R.
Weight reduction by means of intragastric device: experience with the BioEnterics intragastric balloon.
Obes Surg.
2001;
11
519-523
21
Hashiba K, Brasil H A, Wada A M. et al .
Experimental study of an alternative endoscopic method for the treatment of obesity: the butterfly technique [abstract].
Gastrointest Endosc.
2001;
53
AB112
22
Kelleher B, Stone C, Burns M, Gaskill H.
The butterfly procedure for endoluminal treatment of obesity [abstract].
Gastrointest Endosc.
2003;
57
AB186
23
Hashiba K, Hasegawa R T, Wada S. et al .
Plastic device (Butterfly) for endoscopic treatment of obesity: new design and operation [abstract].
Gastrointest Endosc.
2003;
57
AB181
24
Weiner R, Gutberlet H, Bockhorn H.
Preparation of extremely obese patients for laparoscopic gastric banding by gastric-balloon therapy.
Obes Surg.
1999;
9
261-264
25
Doldi S B, Micheletto G, Perrini M N, Rapetti R.
Intragastric balloon: another option for treatment of obesity and morbid obesity.
Hepatogastroenterology.
2004;
51
294-297
26
Awan A N, Swain C P.
Endoscopic vertical band gastroplasty with an endoscopic sewing machine.
Gastrointest Endosc.
2002;
55
254-256
S. C. S. Chung, M. D.
Endoscopy Center, Prince of Wales Hospital · The Chinese University of Hong Kong ·
Shatin, N.T., Hong Kong SAR · China
Fax: +852-2635-0075
eMail: sydneychung@cuhk.edu.hk